16
A network-based gene-weighting approach for pathway analysis.pdf
在许多生物学通路中,基因之间的相对重要性是不完全均一的,而这种不均一性是“组成型”的。他们通过整合蛋白质相互作用数据,基因共表达数据,以及Gene Ontology通路的数据库,构建了一个全基因组水平的基因功能关联网络,并设计了一个度量生物学通路中基因相对重要性的方法。通过对一些已知的生物学通路进行测试的结果表明,该方法计算得到的基因权重和生物学认识是相符的;同一个基因在不同的生物学通路的权重可以不同,因此这些权重是生物学通路特异的;对基因网络的随机干扰试验表明,该方法得到的权重可以对抗相当程度的网络干扰,因而是稳定的。这些权重实际上可以和许多以前发展出来的算法相结合,产生带有基因加权的算法。在该工作中,以两种算法(MeanAbs和GSEA)为例得到了相应的加权版本。
1篇相似文档
6
Gene Manipulation Based Selenium-containing Peptide Exhibiting Synergism of SOD and GPx.pdf
Gene Manipulation Based Selenium-containing Peptide Exhibiting Synergism of SOD and GPx
25
基于GO数据库的MAP3K8基因注释The gene annotation ofMAP3K8 based on GO database.pdf
2.1. 2.1. 2.3GO的工具………………………………………………………………………………… 72.4 实验过程………………………………………………………………………………… 3.实验结果 13
9
variations in gut microbiota and fecal metabolic phenotype associated with depression by 16s rrna gene sequencing and lcms-based metabolomics.pdf
variations in gut microbiota and fecal metabolic phenotype associated with depression by 16s rrna gene sequencing and lcms-based metabolomics
12
Development-and-validation-of-a-gene-expression-based-signature-_2018_The-La.pdf
/oncology Vol 19 March 2018ArticlesLancet Oncol 2018; 19: 382–93Published Online
6
An Improved Method of Gene Synthesis Based on DNA Works Software and Overlap Extension PCR.pdf
ORIGI NAL PAPERAn Improved Method GeneSynthesis Based DNAWorksSoftware OverlapExtension PCRBingxue D
13
Peptide-Mediated Tumor Targeting by a Degradable Nano Gene Delivery Vector Based on Pluronic-Modified Polyethylenimine Nanoscale research letters Wu.pdf
NANOEXPRESS Open AccessPeptide-Mediated Tumor Targetingby DegradableNano Gene DeliveryVector Based P
10
Map-based cloning of the ERECT PANICLE 3 gene in rice.pdf
TheorAppl Genet (2009) 119:1497–1506DOI 10.1007/s00122-009-1151-x123ORI GI NAL PAPERMap-based clonin
25
Expression and gene regulation network of RBM8A in hepatocellular carcinoma based on data mining.pdf
www.aging-us.com423 AGING INTRODUCTION Hepatocellular carcinoma (HCC) topten malignant tumors thirdl

向豆丁求助:有没有gene-based?

如要投诉违规内容,请联系我们按需举报;如要提出意见建议,请到社区论坛发帖反馈。