Elevated CLCX1 expression in breast cancer was associated with TGF-b sigaling

CXCL1 is a chemotactic cytokine shown to regulate breast cancer progression and chemo-resistance.However, the prognostic significance of CXCL1 expression in breast cancer has not been fully characterized. Fibroblastsare important cellular components of the breast tumor microenvironment, and recent studies indicate that this celltype is a potential source of CXCL1 expression i..