PROX1 promotes hepatocellular carcinoma proliferation by b-catenin

Aberrant activation of the Wnt/β-catenin pathway is frequent in hepatocellular carcinoma (HCC) and contributes to HCC initiationand progression. This abnormal activation may result from somatic mutations in the genes of the Wnt/β-catenin pathway and/ordysregulation of the Wnt/β-catenin pathway. The mechanism for the latter remains poorly un..