In-vitro maturation of germinal vesicle and metaphase I eggs prior to cryopreservation optimizes reproductive potential in patients undergoing fertility preservation

Purpose of reviewTo evaluate current and previous findings related to a timely implementation of in-vitro maturation (IVM)of germinal vesicle, metaphase I and metaphase II oocytes with an optimal cryopreservation to determinewhether IVM should be attempted prior to (fresh IVM) or IVM after cryopreservation (postthaw IVM).Mitochondrion, chromatin and spi..