Safety Evaluation of Fucoxanthin purified from Undaria pinnatifida

A toxicity study was conducted on fucoxanthin (FX) purified from Undaria pinnatifida. Evaluation was made following the repeated oral dosing of purified FX (95% purity) to rats for 28 days. In the 28-day, repeated oral dose test, purified FX did not show obvious toxicity. However, significant increases in total cholesterol and high-density lipoprotein..