Viral Clearance Using Traditional, Well-Understood Unit Operations Session 1.2. Anion Exchange Chromatography; and Session 1.3. Protein A Chromatography

Process performance for both AEX (1, 2) and AEXmembrane absorbers (3, 4) is generally effective androbust when performed within a bracketed set of operatingconditions (1). The key process parameters that couldaffect viral clearance for the AEX step include pH,conductivity, resin loading, and reuse cycles.