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13
奥培米芬片 OSPHENA (ospemifene) FDA药品说明书翻译.pdf
奥培米芬片 OSPHENA (ospemifene) FDA药品说明书翻译
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22
ospemifene.pdf
奥培米芬是一种选择性雌激素受体调节剂，用于缓解性交疼痛。推荐剂量为每次60 mg，每日1次，与餐同服；本文收录了销量，化合物及其用途专利等信息；还收录了1条原研路线，3条创新型化学合成路线；奥培米芬的生物学行为是通过与雌激素受体结合介导的，其与ERα位点（Ki=380nM）和ERβ位点（Ki=410nM）相结合；在大鼠（F%=2.6%）和猴（F%=2.7%）中的生物利用度较低；大鼠的MTD>2000 mg/kg。
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3
Ospemifene A Novel Oral Therapy for Vulvovaginal Atrophy of Menopause.pdf
Ospemifene A Novel Oral Therapy for Vulvovaginal Atrophy of Menopause
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12
Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo.pdf
Effects of Ospemifene on Drug Metabolism Mediated by Cytochrome P450 Enzymes in Humans in Vitro and in Vivo
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12
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro.pdf
Differential effects of selective oestrogen receptor modulators (SERMs) tamoxifen, ospemifene and raloxifene on human osteoclasts in vitro
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7
pharmacologic effects of ospemifene in rhesus macaques a pilot study.pdf
pharmacologic effects of ospemifene in rhesus macaques a pilot study
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9
effects of cytochrome p450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene.pdf
effects of cytochrome p450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene
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9
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer.pdf
In vitro and in vivo biologic effects of Ospemifene (FC-1271a) in breast cancer
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7
Female sexual function improved with ospemifene in postmenopausal women with vulvar and vaginal atrophy results of a randomized, placebo-controlled trial.pdf
Female sexual function improved with ospemifene in postmenopausal women with vulvar and vaginal atrophy results of a randomized, placebo-controlled trial
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2
Ospemifene_CAS 128607-22-7_DataSheet_GlpBio.pdf
Ospemifene_CAS 128607-22-7_DataSheet_GlpBioOspemifene_CAS 128607-22-7_DataSheet_GlpBioOspemifene_CAS 128607-22-7_DataSheet_GlpBio
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